This paper shares and contributes to a ground-breaking vision developed and being implemented which consists in the integration of materials modelling methodologies and knowledge-based systems with business process for decision making. The proposed concept moves towards a new paradigm of material and process selection and design by developing and implementing an integrated multi-disciplinary, multi-model and multi-field approach together with its software tool implementation for an accurate, reliable, efficient and cost effective prediction, design, fabricationLife Cycle Engineering (LCE), cost analysis and decision making. This new paradigm of integrated material design is indeed endowed with a great potential by providing further insights that will promote further innovations on a broad scale.